In formally announcing his campaign for the seat of the retiring Voinovich, Ganley is signaling that he is undeterred by the GOP establishment’s support of Rob Portman, a former U.S. House member from the Cincinnati area who later served as a top budget and trade official in the administration of President George W. Bush.

Ganley’s announcement, which he made in his suburban Cleveland hometown of Brecksville, wasn’t a surprise. In March he filed a statement of candidacy and statement of organization.