In HOH’s latest edition of Fictional Franchise — fictional characters and the real people who represent them in Congress — we take on the great villainesses of movies, television and literature.

The tools for misery runs the spectrum, from killing animals to bearing false witness to child abuse.

As for the series, the rules go like this: We decide where a fictional character lives and then look up who represents them in the House. (Learn more here.)

Whether it is physical or psychological torment, these girls got it going on.

Regina George (Rachel McAdams)

“Mean Girls”

Evanston, Ill., Democratic Rep. Jan Schakowsky

We all had a Regina George in high school. She embodies the term “mean girl” and for good reason. Tina Fey based her screenplay on the book “Queen Bees and Wannabes” by Rosalind Wiseman that profiles the behaviors of teenage female non-violent psychopaths.

“She lives in Evanston and though the movie doesn’t specify where exactly, given the size of her house and her lifestyle she’s likely up north, closer to the border of Wilmette, and east, closer to [Lake Michigan],” CQ Roll Call reporter and Wilmette-native Meredith Shiner said.