Sen. Scott Brown (R-Mass.) calls himself the “No.1 target” in a new fundraising e-mail pitch to supporters.

Brown, off the campaign trail for just a month and a half since winning a January special election, is back in action with appearances for Sen. John McCain’s (R-Ariz.) 2010 race Friday and Saturday, as well as the fundraising pitch for his own 2012 re-election.

In his e-mail, Brown writes, “I will need help in the coming 2012 re-election. Because I won office in a Special Election, I will face re-election in less than three short years. I don’t have the luxury of a six year term like most newly-elected Senators!”

“That, coupled with the fact that I will be the #1 target of both the one-party political machine in Massachusetts and liberals all over this country, means we must lay the groundwork now for a winning re-election campaign,” he continues, urging supporters to donate online.

Brown’s not exactly starting from scratch, however. He had a whopping $6 million left over in his bank account after the special election, thanks to a tremendous outpouring of national financial support from Republicans and conservatives in the race’s final days.

National and Massachusetts Democrats are expected to make ending Brown’s Senate career a top priority in 2012.